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  CORD BLOOD BONE MARROW
COLLECTION Painless, noninvasive Invasive and can be quite painful - Collection performed with large needle into hip
RISK TO DONOR None Uncommon (anesthesia related, surgical complications, emergency blood transfusion, etc.)
TIME TO ACQUIRE Days - Units are pre-harvested, median search time is less than one month Difficulty at times tracking down donors who registered, median search time is greater than four months
ACCESS FOR TRANSPLANT Easy - Can be pulled from inventory and shipped within 24 hours Difficult - Donor has to coordinate time off work, transplant team and hospital scheduling must align
NUMBER OF AVAILABLE
CELLS
Less than bone marrow More than cord blood
CHANCES OF GVHD
(Graft Versus Host Disease)
Approximately 10% Serious GVHD occurs in approximately 60% of all unrelated transplants
MEDIAN TIME TO NEUTROPHIL RECOVERY
(The point where the donated cells begin making new cells in the body)
21-35 Days 10-20 Days
ASSOCIATED COSTS Significantly less than bone marrow Significantly more than cord blood
HISTORY First successful transplant in 1988 First successful transplant in 1968
LIKELIHOOD OF FINDING A
MATCH
More likely Less likely